"skin disease of animals," early 15c., from Old French manjue "the itch," also "hunger, appetite; itching, longing," literally "the eating," verbal noun from a collateral form of Old French mangier "to eat" (Modern French manger) "to eat," from Late Latin manducare "to chew, eat," from manducus "glutton," from Latin mandere "to chew" (see mandible).