"plant of the genus Agave," found in deserts of Mexico and southwestern U.S., especially the American aloe, or maguey plant, 1702, from Mexican Spanish, from Nahuatl (Aztecan) mexcalli "fermented drink made from agave," from metl "agave" + ixcalli "stew." Meaning "intoxicating liquor from fermented juice of the agave" is attested in English from 1828. Also the name of a small desert cactus (peyote) found in northern Mexico and southern Texas (1885).