sphingo-
combining form
- used in the names of various related compounds isolated from the brain and nervous tissue[用于从脑和神经组织中分离出来的多种相关化合物的名称]表示“神经”:
-
sphingomyelin.
词源
from Greek Sphinx, Sphing- 'Sphinx', originally in sphingosine, with reference to the enigmatic nature of the compound.
1947 H. E. Carter et al. inJrnl. Biol. Chem. CLXIX. 77Among the lipide constituents there are at least three, the cerebrosides.., sphingomyelins.., and gangliosides.., which are derivatives of the organic base sphingosine. Sphingosine may also be present in other compounds... As a matter of convenience it is proposed that the term sphingolipide be used to designate these substances. [ of nerve tissue]
1978 J. R. Holum Org. &Biol. Chem. xi. 225The acyl units in the acylamido parts of the sphingolipids are not the usual fatty acids found in neutral fats.
1962 Knudson & Kaplan in Aronson & Volk Cerebral Sphingolipidoses 395The sphingolipidoses are hereditary diseases in which there is an accumulation of sphingolipids in one or more tissues of the body... There are at least three enzyme defects among the sphingolipidoses.
1976 Adv. Exper. Med. &Biol. LXVIII. 9 (caption)Examples of early prenatal diagnoses carried out with the present microtechniques in pregnancies at risk for sphingolipidoses.
1883 J. L. W. Thudichum in 12thAnn. Rep. LocalGovt. Board 1882–3:Rep. Med. Officer 1882App. b.No. 3. 221,I have for the purposes of the present research isolated and analysed two representatives of this remarkable class of bodies, one amidomyelin..another sphingomyelin, which was found to be..a genuine educt and principle of the brain.
1920 . [ see cephalin2]
1946 Biol. Rev. XXVI. 285Sphingomyelins are phosphatides in which the sphingosine or a closely related base is bound by an NH{b1}CO linkage to a fatty acid..and by an ester linkage to choline phosphoric acid.
1973 Sphingomyelin . [ see lecithin]
1881 J. L. W. Thudichum in Ann. Chem. Med. II. 18A body remained insoluble which was of an alkaloidal nature, and to which, in commemoration of the many enigmas which it presented to the inquirer, I have given the name of Sphingosin.
1908 Hall & Defren tr. Abderhalden'sText-bk. Physiol. Chem. ii. 20On being subjected to hydrolysis this substance took up two molecules of water and formed one molecule of cerebronic acid, one of sphingosine and one of galactose.
1957 . [ see cerebroside]
1968 A. White et al.Princ. Biochem. (ed. 4) iv. 73Although the above C18 sphingosines are most abundant in sphingolipids, other homologous C16, C17, C19, and C20 sphingosines also are found among the naturally occurring sphingolipids.
ORIGIN: from Greek Sphigg- , Sphigx sphinx , orig. in sphingosine , with ref. to the enigmatic nature of the compound: see -o- .
sphingo-
combining form
Etymology: International Scientific Vocabulary, from Greek sphingein to bind fast — more at sphincter
1. : deflection : bending
< sphingometer >
2. : sphingomyelin
< sphingosine >
1.
< sphingometer >
2.
< sphingosine >