early 15c., "train of followers," from Old French sequelle (14c.), from Late Latin sequela "that which follows, result, consequence," from sequi "to follow, come after, follow after, attend, follow naturally," from PIE root *sekw- (1) "to follow" (cognates: Sanskrit sacate "accompanies, follows," Avestan hacaiti, Greek hepesthai "to follow," Lithuanian seku "to follow," Latin secundus "second, the following," Old Irish sechim "I follow"). Meaning "consequence" is attested from late 15c. Meaning "story that follows and continues another" first recorded 1510s.