1530s, from Latin sedulus "attentive, painstaking, diligent, busy, zealous," probably from sedulo (adv.) "sincerely, diligently," from sedolo "without deception or guile," from se- "without, apart" (see secret) + dolo, ablative of dolus "deception, guile," cognate with Greek dolos "ruse, snare." Related: Sedulously; sedulousness.