"action in resistance or response to another action or power," 1610s, from re- "again, anew" + action, q.v.. Modeled on French réaction, older Italian reattione, from Medieval Latin reactionem (nominative reactio), noun of action formed in Late Latin from past participle stem of Latin reagere "react," from re- "back" + agere "to do, act" (see act, v.).Originally scientific; physiological sense is attested from 1805; psychological sense first recorded 1887; general sense of "action or feeling in response" (to a statement, event, etc.) is recorded from 1914. Reaction time, "time elapsing between the action of an external stimulus and the giving of a signal in reply," attested by 1874.