1520s, from Middle French dexterité (16c.), from Latin dexteritatem (nominative dexteritas) "readiness, skillfulness, prosperity," from dexter "skillful," also "right (hand)" (source of Old French destre, Spanish diestro, etc.), from PIE root *deks- "on the right hand," hence "south" to one facing east (cognates: Sanskrit daksinah "on the right hand, southern, skillful;" Avestan dashina- "on the right hand;" Greek dexios "on the right hand," also "fortunate, clever;" Old Irish dess "on the right hand, southern;" Welsh deheu; Gaulish Dexsiva, name of a goddess of fortune; Gothic taihswa; Lithuanian desinas; Old Church Slavonic desnu, Russian desnoj). The Latin form is with the comparative suffix -ter, thus meaning etymologically "the better direction." Middle English dester meant "right hand," and in heraldry dexter means "on the right side."