late 15c., agent noun from kill, v.. But a surname, Ric[hard] Le Kyller is attested from 1288. Figurative use from 1550s. Meaning "impressive person or thing" is by 1900 (as an adjective, 1979); reduplicated form killer-diller attested by 1938. Killer whale is from 1725; killer instinct is attested from 1931, originally in boxing.